|The Grimm Sisters|
|Persons involved:|| Sabrina Grimm|
|Type of Relationship:||Sisterly|
|Fairy Tale:||Specific to The Sisters Grimm|
|Time in action:||Since 2002 (Daphne's birth)|
|Appearances:|| The Fairy-Tale Detectives|
Daphne brings out a softer and more vulnerable side to Sabrina, as it is mentioned numerous times that Sabrina only got to be as strong as she is, so she could protect Daphne from the instability of the orphanage and their various foster homes. She is Sabrina' literary foil, as she brings out traits in Sabrina's character that would not otherwise be seen. The two sisters do share a very strong bond and Daphne thinks that when they combine their skills "they make a good team".
The sisters' biggest feud occurred when Sabrina stole Daphne's key to the vault where the weapon against the Big Bad Wolf was stored, feeling her little sister was not responsible enough for it. As a result, Daphne stopped sharing a room with Sabrina and barely spoke to her. It took nearly a whole book (The Everafter War) for Daphne to forgive Sabrina, eventually resulting in her moving back into Sabrina's bedroom, commenting that Granny snores while she sleeps. In the two epilogues, the sisters are shown to have retained their close bond; during Sabrina's wedding, Daphne helps Sabrina gets dressed, whilst mentioning that she tried to track Puck but to no avail. It is most likely true that Daphne was Sabrina's maid-of-honour. In the second epilogue, it is also evident that the two share a close bond, and Sabrina writes in her journal fondly of Daphne and the twins that the latter has.